Reports of 67 Cases of New and Severe Adverse Drug Reactions in a Children’s Hospital from 2013 to 2018

Chen Rong

doi:10.13407/ j.cnki.jpp.1672-108X.2022.02.007

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Reports of 67 Cases of New and Severe Adverse Drug Reactions in a Children’s Hospital from 2013 to 2018

更新时间：2022-11-03

- Reports of 67 Cases of New and Severe Adverse Drug Reactions in a Children’s Hospital from 2013 to 2018
- Vol. 28, Issue 2, Pages: 23-26(2022)
- 作者机构：
  
  福建省福州儿童医院,福州,350001
- 作者简介：
- 基金信息：
- DOI：10.13407/ j.cnki.jpp.1672-108X.2022.02.007
  CLC：
- Published：2022，
  
  Published Online：10 February 2022，
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Chen Rong. Reports of 67 Cases of New and Severe Adverse Drug Reactions in a Children’s Hospital from 2013 to 2018. [J]. 28(2):23-26(2022)
DOI：

Chen Rong. Reports of 67 Cases of New and Severe Adverse Drug Reactions in a Children’s Hospital from 2013 to 2018. [J]. 28(2):23-26(2022) DOI： 10.13407/ j.cnki.jpp.1672-108X.2022.02.007.

摘要

目的：分析我院新的、严重药品不良反应（ADR）发生的特点和规律，促进儿童安全合理用药。方法：对我院2013-2018年上报国家药品不良反应监测中心的新的、严重的67例儿童ADR报告进行统计分析。结果：1~3岁儿童患者新的、严重ADR发生率较高，共18例（26.87%）；静脉给药途径引发的ADR最多，共47例（70.15%）；引发新的、严重ADR药物种类主要是抗感染药物，共22例（32.84%），其次是抗肿瘤药物，共12例（17.91%）；ADR累及器官或系统主要为消化系统，共17例（25.37%）。结论：我院需加强ADR监测与上报工作，临床用药过程中需注意监测抗感染药物和静脉用药物引发的ADR，规范给药，促进儿童安全合理用药。

Abstract

Objective: To analyze the characteristics and regularities of new and severe adverse drug reactions (ADR) in our hospital

so as to promote the safe and rational use of drugs for children. Methods: Statistical analysis was performed on reports of 67 cases of new and severe ADR reported to National ADR Monitoring Center in our hospital from 2013 to 2018. Results: The incidence of new and severe ADR was higher in children aged from 1 to 3 years

with a total of 18 cases (26.87%). The most ADR was induced by intravenous administration

with a total of 47 cases (70.15%). The main drug types of new and severe ADR were anti-infective drugs (22 cases

32.84%)

followed by anti-tumor drugs (12 cases

17.91%). Organs or systems involved in ADR were mainly the digestive system

with a total of 17 cases (25.37%). Conclusion: Our hospital needs to strengthen the monitoring and reporting of ADR

pay attention to the monitoring of ADR induced by anti-infective drugs and intravenous drugs in the process of clinical drug use

and promote the safe and rational use of drugs in children.

关键词

不良反应儿童新的严重安全用药

Keywords

adverse drug reactionschildrennewseveresafe drug use

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